elegans and provide first hints about the components responsible for these effects. Our findings highlight the overall anti-aging effects of C.
chinensis compared to the specific positive effects on stress resistance by E. ulmoides, making them good candidates to explain the overall healthspan benefits of C. chinensis extract and its most bioactive fraction, but hardly in E. Furthermore, a hydroxygallic acid derivative and the sterol lipid 4-alpha-formyl-stigmasta-7,24(241)-dien-3-beta-ol are abundantly present in the C. Thus, zingibroside R1 could be (partly) responsible for the observed health benefits of C.
CELLPROFILER 2.2.0 FULL
chinensis extract enriched in zingibroside R1 improved the lifespan, the survival after heat stress, and the locomotion in a manner similar to the full C. Chemical analyses of the extracts revealed the presence of several bioactive compounds such as chlorogenic acid, cinnamic acid, and quercetin. Furthermore, both extracts improved the resistance towards oxidative stress, and decreased the intracellular level of reactive oxygen species. chinensis increased the short-term memory and the mechanosensory response of aged C. We examined the effects of the extracts from two traditional Chinese medicine plants, Cuscuta chinensis and Eucommia ulmoides, on the healthspan of the model organism Caenorhabditis elegans. We hope these changes will make CellProfiler an even better tool for current users and will provide new users better ways to get started doing quantitative image analysis. We’ve also added more explanations to CellProfiler’s settings to help new users get started. We’ve also made changes to CellProfiler’s underlying code to make it faster to run and easier to install, and we’ve added the ability to process images in the cloud and using neural networks (deep learning). In this release, we’ve added the capability to find and measure objects in three-dimensional (3D) images. Pipelines are easy to save, reuse, and share, helping improve scientific reproducibility. Researchers can download an online example workflow (that is, a “pipeline”) or create their own from scratch.
CELLPROFILER 2.2.0 SOFTWARE
The third major release of our free open-source software CellProfiler is designed to help biologists working with images, whether a few or thousands. Thus, many biologists find they need software to analyze images easily and accurately. Looking at the resulting images by eye would be extremely tedious, not to mention subjective. The “big-data revolution” has struck biology: it is now common for robots to prepare cell samples and take thousands of microscopy images.
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